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Apixaban Safety and Efficacy for the Treatment of Venous Thromboembolism in Patients on Dialysis
Friday April 25, 2025 9:10am - 9:25am EDT
Parthenon 2
APIXABAN SAFETY AND EFFICACY FOR THE TREATMENT OF VENOUS THROMBOEMBOLISM IN PATIENTS ON DIALYSIS 
L. Ashton Dickinson, TJ Hodge, Robert Moye, Kimberly Keller, Abby Cowan, Taylor Bird, Ross M. Nesbit 
University of Tennessee Medical Center – Knoxville, TN 
 
Background/Purpose: While there is data in favor of using apixaban for the treatment of acute venous thromboembolism (VTE) in patients with End Stage Renal Disease (ESRD), more data is needed to inform safe and efficacious dosing in this population. This study evaluated the safety and efficacy outcomes of various apixaban dosing strategies for acute VTE in adult hospitalized patients with ESRD on dialysis.    
Methodology: This was a single-center, retrospective analysis that drew data from dialysis patients who experienced an acute VTE between the period of January 2016 and December 2023. Groups compared included patients who received apixaban 10 mg BID for 7 days (full lead-in dosing) with 5 mg BID thereafter to patients who received apixaban 10 mg BID for 0-6 days (modified lead-in dosing) with 5 mg BID thereafter. Patients > 18 years with ESRD on maintenance dialysis (hemodialysis or peritoneal) and a newly diagnosed acute VTE receiving anticoagulation therapy with apixaban were included in this study. Primary endpoints collected comprised of&n
Presenters
LA

Luren Ashton Dickinson

PGY1 Pharmacy Resident, University of Tennessee Medical Center
Dr. Dickinson grew up in Cumming, Georgia. She obtained a Bachelor of Science in Biology and later a Doctor of Pharmacy degree from the University of Georgia. Next year, she will be participating in the PPD Clinical Research and Drug Development Fellowship at the University of North... Read More →
Evaluators
avatar for Jason Dover

Jason Dover

PGY-1 Residency Program Director, Clinical Pharmacist Emergency Medicine/Internal Medicine, East Alabama Medical Center
Friday April 25, 2025 9:10am - 9:25am EDT
Parthenon 2
  Internal Medicine (IM), University of Tennessee Medical Center
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