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Exploring the Analgesic Efficacy of Ketamine in the Management of Traumatic Injuries
Thursday April 24, 2025 11:00am - 11:15am EDT
Athena I
Title: Exploring the Analgesic Efficacy of Ketamine in the Management of Traumatic Injuries 
Authors: Aubrey N. Baker, Jordan Spurling, John Patka, Shauntrell Johnson 
Objective: Discuss the use of ketamine in patients with a traumatic injury
Self Assessment Question: What are potential reasons for using ketamine in patients with traumatic injury?
Background: Acute pain is a common complication experienced by trauma patients. Inadequate treatment of acute pain after trauma delays return to work, impairs quality of life and increases the risk of complications such as post-traumatic stress disorder. Although opioids have been the mainstay of treatment, providers have been looking for alternative analgesic agents. Ketamine has analgesic effects and can be beneficial for trauma patients due to its potential beneficial effects on blood pressure and minimal effects on respiratory drive. The purpose of this study is to assess the efficacy of ketamine in patients who have sustained a traumatic injury. 
Methods: This study was a single center retrospective chart review conducted at a level 1 trauma center. Patients were included if they presented between December 2023 through February 2024, ≥ 18 years old, and received an initial ketamine dose ≤ 50 mg. Patients were excluded if they had a Glasgow Coma Score ≤ 8, were on outpatient opioid therapy, or if they were admitted for an acute behavioral emergency.  Patients presenting December through January were included if missing preceding or post ketamine administration pain score. However, patients in the month of February were only included if they had documented pain scores for both a preceding and post ketamine administration. Pain scores prior to ketamine administration was defined as a pain score documented within an hour including a 15-minute leniency period prior to administration. Furthermore, the institutional guidelines require documentation of pain score on arrival to ED and 60-minutes after analgesic administration. The primary outcome of this project is to compare the difference in pain scores from the initial ketamine dose to the next pain score. The secondary outcome is reviewing ketamine dosing for pain based on internal guidelines. Data analysis included the Wilcoxon rank sum test, repeated ANOVA measures 
Moderators
VV

Vanessa Velazco

Critical Care Pharmacist, Williamson Medical Center
Presenters
AB

Aubrey Baker

PGY-2 Emergency Medicine Resident, Grady Memorial Hospital
Aubrey Baker, PharmD, is a PGY-2 Emergency Medicine Pharmacy Resident. She received her Doctor of Pharmacy from the University of Georgia College of Pharmacy and completed her PGY-1 pharmacy residency at Phoebe Putney Memorial Hospital. Her professional subspecialty interests within... Read More →
Evaluators
avatar for Adam Sawyer

Adam Sawyer

PGY1 & PGY2 Critical Care Residency Program Director, Huntsville Hospital
Thursday April 24, 2025 11:00am - 11:15am EDT
Athena I
  Critical Care/Emergency Medicine (CCM), Grady Memorial Hospital
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