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Impact of an Antimicrobial Stewardship Bundle on the Treatment of Urinary Tract Infections in Older Adults
Friday April 25, 2025 11:20am - 11:35am EDT
Athena A
Title: Impact of an Antimicrobial Stewardship Bundle on the Treatment of Urinary Tract Infections in Older Adults
Authors: Elly R. Sherman, PharmD; Maria Muehrcke, PharmD, MBA, BCPS; Laura Bobbitt, PharmD, BCIDP
Objective: To assess how antimicrobial prescribing changed after the implementation of a geriatrics-specific antimicrobial stewardship bundle
Background: Urinary tract infections (UTIs) are a common indication for hospital admission in geriatric patients. However, these infections are often misdiagnosed, especially in patients with altered mental status. The risks of overtreating UTIs include the development of antimicrobial resistance and adverse drug effects, including C. difficile colitis. Many institutions, including Vanderbilt University Hospital (VUH), have implemented antimicrobial stewardship initiatives in response to these risks. This retrospective, single-center analysis aims to assess how antimicrobial prescribing changed after the implementation of a geriatrics-specific antimicrobial stewardship bundle at VUH. 
Methods: Included patients were ≥65 years of age, admitted to the geriatrics teaching service, and had a urinalysis ordered during admission. Patients with a neurogenic bladder, altered urologic anatomy, concomitant infection, who were receiving antibiotics immediately prior to admission, were neutropenic, or transitioned to comfort care within 48 hours of admission were excluded. The primary outcome was days of antimicrobial therapy per 1000 patient days. Secondary outcomes included rates of discontinuation of antibiotic therapy in asymptomatic bacteriuria, duration of therapy, rates of C. difficile colitis within 90 days, and proportion of patients with an inappropriate UTI diagnosis.
Results: In progress
Conclusions: In progress
Moderators
BK

Brian Knott

Clinical Pharmacy Supervisor, AdventHealth Winter Park
Presenters
avatar for Elly Sherman

Elly Sherman

PGY1 Pharmacy Resident, Vanderbilt University Medical Center
Elly is a current PGY1 Pharmacy Resident at Vanderbilt University Medical Center in Nashville, TN and will be staying on to complete her PGY2 in Infectious Diseases. She completed her undergraduate coursework and Doctor of Pharmacy degree at the University of Georgia and is excited... Read More →
Evaluators
CL
Friday April 25, 2025 11:20am - 11:35am EDT
Athena A
  Infectious Disease (ID), Vanderbilt University Medical Center
  • global Y
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